Multi phenotype screen™ is a proprietary process technology of ExoCan which allows for estimation of multiple tumor cell parameters in just one test e.g. cell growth, cell migration, cell-cell interactions. Multi phenotype screen™ facilitate identification of anti-tumor molecules/drugs with multifaceted activity under in vitro screens. The potential applications and benefits are drug repurposing, faster drug-like candidate identification, and cost cuttings for hit generation. Multi phenotype screen™ can be used for initial bioactivity testing of small molecules/repurposed drugs, hit identification from a small library of molecules, hit-to-lead generation for obtaining smarter anti-tumor molecules, and pathway discovery in oncology.